Neurome, Inc. - Publications

Quantitative Neuroanatomy :

Wu, CC, Reilly, JF, Young, WG, Morrison, JH and Bloom, FE. (2004)
High-throughput morphometric analysis of individual neurons.
Cerebral Cortex. 14(5): 543-554, 2004.
ABSTRACT

Wu, CC, Chawla, F, Games, D, Rydel, RE, Freedman, D, Schenk, D, Young, WG, Morrison, JH and Bloom, FE. (2004)
Selective vulnerability of dentate granule cells prior to amyloid deposition in PDAPP mice: Digital morphometric analyses.
Proc Natl Acad Sci U S A. 101: 7141-7146, 2004.
HTML | PDF | ABSTRACT

Broide, RS, Trembleau, A, Ellison, J, Cooper, J, Lo, D, Young, WG, Morrison, JH, Bloom, FE. (2004)
Standardized quantitative in situ hybridization using radioactive oligonucleotide probes for detecting relative levels of mRNA transcripts verified by real-time PCR
Brain Research. 1000: 211-222, 2004.
ABSRACT

Reilly, JF, Games, D, Rydel, RE, Freedman, S, Schenk, D, Young, WG, Morrison, JH and Bloom, FE. (2003)
Amyloid deposition in the hippocampus and entorhinal cortex: Quantitative analysis of a transgenic mouse model.
Proc Natl Acad Sci U S A. 100: 4837-4842, 2003.
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Redwine, JM, Kosofsky, B, Jacobs, RE, Games, D, Reilly, JF, Morrison, JH, Young, WG, and Bloom, FE. (2003)
Dentate gyrus volume is reduced before onset of plaque formation in PDAPP mice: a magnetic resonance microscopy and stereologic analysis.
Proc Natl Acad Sci U S A. 100: 1381-1386, 2003.
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TOGA:

Gavrilyuk V, Kalinin S, Hilbush BS, Middlecamp A, McGuire S, Pelligrino D, Weinberg G, Feinstein DL. (2005)
Identification of complement 5a-like receptor (C5L2) from astrocytes: characterization of anti-inflammatory properties.
J Neurochem. 92(5): 1140-9, 2005

Liang T, Habegger K, Spence JP, Foroud T, Ellison JA, Lumeng L, Li TK, Carr LG. (2004)
Glutathione S-transferase 8-8 expression is lower in alcohol-preferring than in alcohol-nonpreferring rats.
Alcohol Clin Exp Res. 28(11): 1622-8, 2004

Carson, MJ, Thrash, JC and Lo, D. (2004)
Analysis of microglial gene expression: Toward targeted therapies for CNS neurodegenerative and autoimmune disease.
Amer. J. Pharmacogenomics. 4(5): 321-30, 2004. Review

Spence, J, Liang, T, Foroud, T, Lo, D and Carr, LG. (2004)
Total Gene Expression Analysis (TOGA): A complementary approach to QTL analysis in selected rat strains.
Addiction Biology. 10: 47-51, (2005)

Bader AG, Felts KA, Jiang N, Chang HW, Vogt PK. (2003)
Y box-binding protein 1 induces resistance to oncogenic transformation by the phosphatidylinositol 3-kinase pathway.
Proc Natl Acad Sci U S A. 100(21): 12384-9, 2003

Wieland SF, Vega RG, Muller R, Evans CF, Hilbush B, Guidotti LG, Sutcliffe JG, Schultz PG, Chisari FV. (2003)
Searching for interferon-induced genes that inhibit hepatitis B virus replication in transgenic mouse hepatocytes.
J Virol. 77(2): 1227-36, 2003

Thomas, EA, George, R, Danielson, P, Nelson, PA, Warren, AJ, Lo, D and Sutcliffe, JG. (2003)
Antipsychotic drug treatment alters expression of mRNAs encoding lipid metabolism-related proteins.
Molecular Psychiatry. 8: 983-93, 2003.

Liang, T, Spence, J, Liu, L, Strother, WN, Chang, HW, Ellison, JA, Lumeng, L, Li, TK, Foroud, T and Carr, LG. (2003)
alpha-Synuclein maps to a quantitative trait locus for alcohol preference and is differentially expressed in alcohol-preferring and -nonpreferring rats.
Proc Natl Acad Sci U S A. 100: 4690-5, 2003.

Schmid CD, Sautkulis LN, Danielson PE, Cooper J, Hasel KW, Hilbush BS, Sutcliffe JG, Carson MJ. (2002)
Heterogeneous expression of the triggering receptor expressed on myeloid cells-2 on adult murine microglia.
J Neurochem. 83(6): 1309-20, 2002.

Lo, D, Hilbush, B, Mah, S, Brayden, D, Byrne, D, Higgins, L and O'Mahony, D. (2002)
Catching target molecules for drug delivery using TOGA gene expression profiling.
Adv. Drug Del. Rev. 54: 1213-1223, 2002.

Lo, D, Hilbush, B, O'Mahony, D, and Sutcliffe, JG. (2002)
Open system gene expression profiling and identification of novel genes for targeted vaccine delivery.
Expert Rev. Vaccines. 1: 95-100, 2002.

Shao Y, Akmentin W, Toledo-Aral JJ, Rosenbaum J, Valdez G, Cabot JB, Hilbush BS, Halegoua S. (2002)
Pincher, a pinocytic chaperone for nerve growth factor/TrkA signaling endosomes.
J Cell Biol. 157(4): 679-91, 2002.

Hilbush, BS, Lo, D, Chen, L and Sutcliffe, JG. (2002)
TOGA: Total gene expression analysis.
In "Analysing Gene Expression,". S. Lorkowski and P. Cullen, eds. (Wiley-VCH, Weinheim, 2002). 529-537, 2002.

Lo, D. (2002)
Modern genetics research: Will it change the practice of medicine?
Whittier Law Review. 24(2): 374-383, 2002.

Sutcliffe, JG. (2001)
Open-System Approaches to Gene Expression in the CNS.
Journal of Neuroscience. 21(21): 8306-8309, 2001.

Lo, D, Hilbush, B and Sutcliffe, JG. (2001)
TOGA analysis of gene expression to accelerate target development.
European Journal of Pharmaceutical Sciences. 14: 191-196, 2001.

Thomas, EA, Dean, B, Pavey, G and Sutcliffe, JG. (2001)
Increased CNS levels of apolipoprotein D in schizophrenic and bipolar subjects: Implications for the pathophysiology of psychiatric disorders.
Proc Natl Acad Sci U S A. 98: 4066-4071, 2001.

Thomas EA, Danielson PE, Nelson PA, Pribyl TM, Hilbush BS, Hasel KW, Sutcliffe JG. (2001)
Clozapine increases apolipoprotein D expression in rodent brain: towards a mechanism for neuroleptic pharmacotherapy.
J Neurochem. 76(3): 789-96, 2001.

Sutcliffe, JG, Foye, PE, Erlander, MG, Hilbush, BH, Bodzin, LJ, Durham, JT and Hasel, KW. (2000)
TOGA: An automated parsing technology for analyzing expression of nearly all genes.
Proc Natl Acad Sci U S A. 97: 1976-1981, 2000.

Vaccine:

Lo, D. (2004)
Exploiting immune surveillance mechanisms in mucosal vaccine development.
Expert Opin. Biol. Therapy. 4: 397-406, 2004.

Lo, D, Tynan, W, Dickerson, J, Scharf, M, Cooper, J, Byrne, D, Brayden, D, Higgins, L, Evans, C and O'Mahony, DJ. (2004)
Cell culture modeling of specialized tissue: Identification of genes expressed specifically by Follicle Associated Epithelium of Peyer's Patch by expression profiling of Caco-2/Raji co-cultures.
Intl. Immunol. 16: 91-99, 2004.

Lo, D, Tynan, W, Dickerson, J, Mendy, J, Chang, H-W, Scharf, M, Byrne, D, Brayden, D, Higgins, L, Evans, C and O'Mahony, DJ. (2003)
Peptidoglycan recognition protein expression in mouse Peyer's patch Follicle Associated Epithelium suggests functional specialization.
Cell. Immunol. 224: 8-16, 2003.